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Ahmed A Samatar Selected Research

SCH772984

1/2018Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.
11/2016Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma.
1/2016Dissecting Therapeutic Resistance to ERK Inhibition.
7/2013Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.

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Ahmed A Samatar Research Topics

Disease

11Neoplasms (Cancer)
10/2021 - 08/2002
7Melanoma (Melanoma, Malignant)
01/2018 - 07/2013
1Breast Neoplasms (Breast Cancer)
10/2021
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2016
1Substance-Related Disorders (Drug Abuse)
02/2015
1Carcinogenesis
08/2002

Drug/Important Bio-Agent (IBA)

6Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
01/2016 - 07/2013
4SCH772984IBA
01/2018 - 07/2013
2MK-8353IBA
07/2018 - 01/2018
2Mitogen-Activated Protein KinasesIBA
07/2013 - 01/2013
2Messenger RNA (mRNA)IBA
04/2006 - 08/2002
1Hormones (Hormone)IBA
10/2021
1Estrogen ReceptorsIBA
10/2021
1Estrogens (Estrogen)FDA Link
10/2021
13(S)-thiomethyl pyrrolidineIBA
07/2018
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2016
1RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
04/2006
1LigandsIBA
04/2006
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
04/2006
1Transforming Growth Factor beta (TGF-beta)IBA
08/2002

Therapy/Procedure

6Therapeutics
10/2021 - 05/2015